Walgreens Hilton Head

The Walgreens Pharmacy sign over the Island Crossing store on Palmetto Bay Road, Hilton Head Island

Hilton Head has two Walgreens: Island Crossing on the south end, open to midnight, and Hatton Place on the north end.

  • Stores: two on the island
  • Latest: Island Crossing to midnight
  • Sunday pharmacy: none on the island

Walgreens on Hilton Head Island

Walgreens has two stores on Hilton Head. Island Crossing, at 11 Palmetto Bay Road beside the Publix by Sea Pines Circle, is the south-end store, open 7 a.m. to midnight every day. Hatton Place, at 20 Hatton Place on the north end, is open 8 a.m. to 9 p.m.

The pharmacy counters keep much shorter hours than the stores. Island Crossing’s pharmacy is open 10 to 6, Monday to Saturday, and closed on Sunday. Hatton Place’s is open 9 to 6 on weekdays only. Neither Walgreens pharmacy is open on Sunday, so for a Sunday prescription use CVS, Publix at Festival Centre, Kroger or Burke’s; our Hilton Head pharmacy guide has their hours.

Is There a 24-Hour Walgreens Near Hilton Head?

No. Island Crossing used to be listed as a 24-hour store, and some websites still say so, but it closes at midnight. The Walgreens stores in Bluffton and Savannah are not open around the clock either. After midnight, the only medical help on the island is the Hilton Head Medical Center emergency room.

Both stores offer prescription delivery and curbside pickup, and a Walgreens customer from home can have a prescription filled here from the app.

Walgreens Hilton Head Stores

South end, by Sea Pines Circle

Walgreens, Island Crossing

The Walgreens at Island Crossing on Palmetto Bay Road

The south-end Walgreens in the Island Crossing center beside Publix, a few minutes from Sea Pines, Coligny and Shipyard.

  • 11 Palmetto Bay Rd Ste 110, Hilton Head Island, SC 29928
  • (843) 686-6525
  • Store, every day: 7 a.m. to midnightPharmacy: Mon to Sat 10 to 6; closed Sunday
Get directions

North end, off William Hilton Parkway

Walgreens, Hatton Place

The Walgreens store at 20 Hatton Place

The north-end Walgreens, near the hospital, Main Street and Hilton Head Plantation. Its pharmacy is closed on Saturday and Sunday.

  • 20 Hatton Pl, Hilton Head Island, SC 29926
  • (843) 342-7451
  • Store, every day: 8 a.m. to 9 p.m.Pharmacy: Mon to Fri 9 to 6; closed 1:30 to 2 and on weekends
Get directions

More Hilton Head Pharmacies

Hilton Head pharmacies

Every pharmacy on Hilton Head Island by area, with pharmacy hours, Sunday and late-night options, free island delivery and prescription transfers.

CVS Hilton Head Island

CVS on Hilton Head Island has two stores: Pope Avenue, open to midnight with a MinuteClinic, and Mathews Drive. Store and pharmacy hours and phones.

Hilton Head hospital and urgent care

Hilton Head's hospital and 24-hour ER, every island urgent care clinic, the nearest hospitals off the island, and what to do in an emergency.

Hilton Head grocery stores

Hilton Head grocery stores by area: Publix, Harris Teeter, Kroger, Walmart, The Fresh Market and the Coligny Piggly Wiggly, plus grocery delivery.

Frequently Asked Questions

How many Walgreens are on Hilton Head Island?

Two: Island Crossing at 11 Palmetto Bay Road on the south end, and Hatton Place at 20 Hatton Place on the north end.

Is the Walgreens on Hilton Head open 24 hours?

No. The Island Crossing store is open 7 a.m. to midnight and Hatton Place 8 a.m. to 9 p.m.

Is the Walgreens pharmacy on Hilton Head open on Sunday?

No. Island Crossing’s pharmacy is closed on Sunday and Hatton Place’s on both weekend days.

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