Main Street Medical, Hilton Head

The front entrance of Main Street Medical on Main Street, Hilton Head Island

A north-end urgent care and family practice on Main Street, with walk-ins seven days a week, X-rays and an in-house lab.

Walk-ins
seven days a week
On site
X-ray and lab
Patients
adults and children

Urgent Care and Family Practice on Main Street

Main Street Medical is a locally owned practice on the north end of Hilton Head that works as both an urgent care clinic and a family doctor’s office. Walk-ins and appointments are both taken seven days a week. It treats adults and children, and has digital X-ray and an in-house lab, so a suspected fracture or a strep test can be handled in one visit.

It was founded by Dr. Joel Johnson III, a board-certified emergency physician, and its team of doctors and nurse practitioners also does school, sports, employment and DOT physicals, drug screens, weight-loss care and dermatology. Patients praise unhurried visits and doctors who explain clearly.

Where Main Street Medical Is

The clinic is at 93 Main Street, off William Hilton Parkway just inside the north end of the island, about five minutes from Hilton Head Plantation and Indigo Run and close to the hospital. The practice also uses a second suite across the street at 88 Main Street. Its weekend hours are shorter than weekdays, so call before driving over late in the day.

More Medical Care on Hilton Head

Hilton Head's hospital and 24-hour ER, every island urgent care clinic, the nearest hospitals off the island, and what to do in an emergency.

Novant Health Hilton Head Medical Center, formerly Hilton Head Hospital: the island's only hospital and 24-hour ER. Address, phone and trauma care.

Novant Health Urgent Care on Hilton Head, formerly Doctors Care: the mid-island walk-in clinic open until 8 p.m. on weekdays. Address, hours, phone.

Every pharmacy on Hilton Head Island by area, with pharmacy hours, Sunday and late-night options, free island delivery and prescription transfers.

Frequently Asked Questions

Does Main Street Medical take walk-ins?

Yes. It takes walk-ins and scheduled appointments seven days a week. Call (843) 681-3777 to check the day’s hours.

Is Main Street Medical urgent care?

Yes, and a family practice too: it treats walk-in illnesses and injuries and also sees regular primary care patients, adults and children.

Does Main Street Medical have X-rays?

Yes. It has digital X-ray and an in-house lab on site.

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